解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::The entry modes of Japanese encephalitis (JE) and dengue-2 (DEN-2) viruses into C6/36 mosquito cells and of DEN-2 virus into human peripheral blood monocytes in vitro were studied. Inoculation of either JE or DEN-2 virions into C6/36 cells resulted in direct penetration of the virions into the cytoplasm at the cell su...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01313814
更新日期:1989-01-01 00:00:00
abstract::A physical map for the genome of Spodoptera littoralis (Egyptian cottonworm) nuclear polyhedrosis virus of B-type (S1MNPV-B) [Cherry CL, Summers MD (1985) J Invertebr Pathol 46: 289-295] was prepared using the restriction endonucleases SmaI, SfiI, NotI, ApaI, KpnI, BstEII, PstI, SacI, and HindIII. The size of the geno...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01313815
更新日期:1989-01-01 00:00:00
abstract::Euthymic (SD or outbred rnu/+) and athymic (rnu/rnu) rats were inoculated oronasally or intraperitoneally with the RV-Y strain of rat virus when they were 2 days or 4 weeks old. Clinical signs of infection in athymic infants were similar to those in euthymic infants, but significantly more athymic infants died. Some i...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01311362
更新日期:1989-01-01 00:00:00
abstract::In order to improve the knowledge of the humoral immune response to CMV infection, we developed an immunoblotting technique which allowed a better analysis of the changes in the pattern of anti CMV-polypeptides IgM. We examined 234 sera belonging to 27 renal allograft recipients developing a primary or recurrent CMV i...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310938
更新日期:1989-01-01 00:00:00
abstract::Retrovirus infectivity is the result of a cooperative interaction of three structural genes, gag, pol, and env. Since the L-cell endogenous retrovirus (LCV) lacks the env gene translation product, our aim was to study the biological and molecular basis of its non-infectiousness. Fusion experiments between LCV and homo...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01315566
更新日期:1988-01-01 00:00:00
abstract::Herpes simplex virus type 2 (HSV-2), strain YS-4 C-1, isolated by plaque cloning from a clinical isolate was found to be resistant to acyclovir (ACV; acycloguanosine) in vitro. It was sensitive to phosphonoacetic acid and 9-beta-D-arabinofuranosyladenine. Thymidine kinase (TK) activity of YS-4 C-1 was less than 1% of ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310998
更新日期:1988-01-01 00:00:00
abstract::The chemical nature of the binding sites for vesicular stomatitis virus (VSV) was studied by measuring the ability of solubilized rat brain cell membranes (SRBM) to compete with cultured cells for viral binding. SRBM significantly reduced both binding and infectivity of VSV. After separation of protein and lipid compo...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01311075
更新日期:1988-01-01 00:00:00
abstract::Immunofluorescence assay using monospecific and monoclonal antibodies to the 65 K major protein of human cytomegalovirus (HCMV) was carried out to monitor the expression of this protein in infected cells. Regardless of differences in the reactivity of the monoclonal antibodies, as determined by immunoblotting and immu...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01314653
更新日期:1988-01-01 00:00:00
abstract::Isolates of bovine viral diarrhea (BVD) virus were differentiated by monoclonal antibodies (MoAbs) reactive with the 56 kD viral polypeptide. Patterns of neutralizing activity of the MoAbs indicate that multiple epitopes are involved in virus neutralization. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01311029
更新日期:1988-01-01 00:00:00
abstract::Herpes simplex virus type 1 (HSV-1) infection in mutant mice with severe combined immunodeficiency (SCID mice), i.e., mice in which the differentiation of both T and B lymphocytes is severely impaired, was studied. All control (infected and not treated with antibodies or with immune spleen cells) SCID mice were dead b...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01319810
更新日期:1988-01-01 00:00:00
abstract::Trigeminal ganglia from swine latently infected with pseudorabies virus (PRV) were examined for the presence of PRV nucleic acids by in situ hybridization. Both viral DNA and RNA were detectable in latently infected neurons, indicating that the PRV genome is transcriptionally active during the latent phase of infectio...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01321010
更新日期:1988-01-01 00:00:00
abstract::The synthesis of M protein of HVJ (Sendai virus) in rat glioma (C6) cells, as has previously been reported, is selectively reduced at a nonpermissive temperature of 39 degrees C. In this phenomenon no difference was found in the viral RNA synthesis and the stability of the viral RNAs between the permissive and nonperm...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310830
更新日期:1988-01-01 00:00:00
abstract::Two group A rotaviruses (ISU-64 and ISU-65) with subgroup I antigen were isolated from pigs with diarrhea and were shown by two-way neutralization tests to be two new serotypes of porcine rotavirus. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310917
更新日期:1988-01-01 00:00:00
abstract::Six isolates of Suid herpesvirus 1 (SHV-1) collected from clinical outbreaks of Aujeszky's disease (AD) in Jutland in January-February, 1985, were compared by restriction fragment pattern (RFP) analyses with older SHV-1 isolates from Jutland as well as with SHV-1 isolates from different parts of West Germany and Irela...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310912
更新日期:1988-01-01 00:00:00
abstract::The base sequences of the coding region of the nucleoprotein (NP) genes of two H 10 influenza A viruses, one avian (virus N) and one mink virus, have been determined by primer extension. When the NP genes and the NP sequences derived from the only open reading frame of the two H 10 viruses were compared with those of ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01319816
更新日期:1988-01-01 00:00:00
abstract::Mouse hepatitis virus 3 (MHV-3) is highly hepatotropic in sensitive mice. Temperature-sensitive mutants (ts mutants) induced by N-methyl-N'-nitrosoguanidine and 5-fluorouracil were isolated. Twelve mutants which were able to induce the formation of syncytia at 33 degrees C but not at the restrictive temperature (39.5 ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01487679
更新日期:1988-01-01 00:00:00
abstract::The polypeptides associated with fowlpox virus (FPV) infection of chicken embryo skin (CES) cells were examined by metabolic labelling with [35S]-methionine and sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE). Polypeptide synthesis was followed over the first 48 hours post infection, as this was s...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01320959
更新日期:1987-01-01 00:00:00
abstract::Four geographic variants (topotypes) of yellow fever (YF) virus from Africa and South America previously determined by RNA oligonucleotide mapping were analyzed for their structural, antigenic and virulence characteristics. The electrophoretic migration mobility and carbohydrate content of the envelope protein E chara...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310727
更新日期:1987-01-01 00:00:00
abstract::A simultaneous decay of the expression of Im 140 kDa, Im 150 kDa and Im 160 kDa high MW membrane antigens, concomitant with the cell proliferation arrest, was observed during erythropoietin induced differentiation of ts 34 AEV-transformed erythroid cells cultivated at the restrictive temperature. Expression of embryo-...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310975
更新日期:1987-01-01 00:00:00
abstract::We have prepared monoclonal antibodies to each of the enteric adenoviruses types 40 and 41. Three different hybridoma cell lines were selected which produced antibody found to react by radioimmunoprecipitation with adenovirus (Ad) hexon antigens. One was specific for Ad 40, another for Ad 41, and a third one reacted w...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310718
更新日期:1987-01-01 00:00:00
abstract::It is shown that reovirus capsid inner layer consists of 132 capsomeres with a skewed icosahedral pattern of T = 13 (left). 780 structural units composing capsomeres are integrated into trimers. The boundary between capsomeres runs between the structural units forming trimers. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01313903
更新日期:1987-01-01 00:00:00
abstract::Gangliosides from different cells were tested for their inhibiting activity on VSV attachment to CER cells and goose erythrocytes. This inhibiting activity was enhanced when gangliosides were inserted into liposomes, in particular if containing phosphatidylserine. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310981
更新日期:1987-01-01 00:00:00
abstract::Newborn WKA rats given a single intraperitoneal injection of MMC treated TARS-1, a rat T cell line producing HTLV-I, were shown to accumulate high titred antibodies specific for HTLV-I. Adult WKA rats rejected TARS-1 transplant with transient appearance of anti-HTLV-I antibodies. However, rats maintained under daily a...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01314420
更新日期:1987-01-01 00:00:00
abstract::HSV-2 infections suppress the antibody response to HSV-1 but do not impair the mouse cytomegalo virus (MCMV) antibody generating system. In contrast, the sheep red blood cell (SRBC) IgM response is impaired by preinfections with HSV-2 but not with HSV-1. From the time kinetics of this suppression it can be concluded t...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310741
更新日期:1987-01-01 00:00:00
abstract::We have examined by immunofluorescent antibody staining technique the expression of herpes simplex virus type 1 (HSV-1) in organ cultures of the normal human oral mucosa. The expression of HSV-1 antigen was found selectively in the epithelial cell layers in relatively undifferentiated states such as basal layer and lo...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310061
更新日期:1987-01-01 00:00:00
abstract::Adult Balb/c mice were passively immunized with monoclonal antibodies (100 micrograms/mouse) raised against tick-borne encephalitis (TBE) virus then challenged 24 hours later s.c. with 10 LD50 of TBE virus (Nëudorfl isolate). None of the mice showed evidence of premature death although all except one of the monoclonal...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310983
更新日期:1987-01-01 00:00:00
abstract::We have sequenced the coxsackievirus A 21 polymerase gene and 3' noncoding region. The sequence is 98 per cent homologous at the amino acid level to the three poliovirus serotypes. This is comparable to the relationship between polioviruses and indicates a recent evolutionary divergence of the viruses. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01313732
更新日期:1987-01-01 00:00:00
abstract::Monensin, at concentrations which depended on the multiplicity of infection, was found to prevent DNA replication of human cytomegalovirus (HCMV) as well as production of viral progeny in human foreskin fibroblasts. The drug did not affect DNA replication of herpes simplex virus. Inhibition of consecutive HCMV DNA syn...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310716
更新日期:1987-01-01 00:00:00
abstract::The numbers of the carbohydrate side chains have been analyzed on a series of subtype 7 hemagglutinins of influenza A virus. The procedure employed involves growth of the virus in the presence of the trimming inhibitor N-methyl-1-desoxynojirimycin followed by controlled removal of the resulting mannose-rich oligosacch...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01314433
更新日期:1987-01-01 00:00:00
abstract::Human papillomavirus (HPV) type 13 DNA was detected in focal epithelial hyperplasia lesions of the oral mucosa in seven half-caste mexicans. The lesions contained intracellular papillomavirus-like particles with a diameter of about 50 nm. DNA extracted from biopsies contained unintegrated HPV type 13 DNA genomes as re...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01313899
更新日期:1987-01-01 00:00:00
abstract::The 87,000-dalton glycoprotein (gp87) of bovine herpesvirus type 1 (BHV-1) was found to selectively attach to susceptible cells. The attachment of gp87 to the cells was markedly decreased by the prior adsorption of intact virions. Anti-gp87 (site Ia) monoclonal antibody, which inhibited BHV-1 adsorption to the cells a...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01314428
更新日期:1987-01-01 00:00:00
abstract::Highly purified virulent poliovirus preparations harbour an endogenous protein kinase. Enzyme activity increases significantly upon purification of infectious virus particles from infected HeLa cells. Enzyme activity is stimulated by divalent cations. The substrate specificity and the degree of stimulation of the kina...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01311330
更新日期:1987-01-01 00:00:00
abstract::The genomic RNA of infectious flacherie virus (IFV), an insect picornavirus, was shown to contain a covalently attached substance which can be labeled with 125I-Bolton and Hunter reagent. This substance was found to be a protein covalently linked to the virus genome, because it cosedimented and was copurified with the...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01317378
更新日期:1986-01-01 00:00:00
abstract::Two independent isolates of an unusual type of rotavirus were obtained from over 900 faecal samples obtained from piglets with diarrhoea. Genome profiles, containing eleven segments, were not characteristic of group A electropherotypes and corresponded to an atypical virus. The profiles were, however, distinct from th...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01309892
更新日期:1986-01-01 00:00:00
abstract::A non-neutralizing monoclonal antibody (YO-60) against human rotavirus was found to be directed to VP2 (90,000-dalton protein), one of the two major components of the inner capsid. The reactivity patterns of the YO-60 antibody were very similar, though not identical, to those of subgroup II-specific YO-5 monoclonal an...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310550
更新日期:1986-01-01 00:00:00
abstract::Persistent infection with human cytomegalovirus (HCMV) can be established in cultures of human ovarian teratocarcinoma (PA1) cells, and maintained for more than 200 days. Infected cultures maintained at 34 degrees C (PA1CMV34) and 37 degrees C (PA1CMV37) entered crisis and subsequently displayed massive cytopathic eff...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01316737
更新日期:1986-01-01 00:00:00
abstract::RNase resistance analyses of native, heat-denatured and self-annealed L and S species of Machupo virion RNA revealed the presence of complementary sequences. Self-annealing was concentration-dependent. The data indicate, that complementary sequences were present in separate RNA strands. ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310900
更新日期:1986-01-01 00:00:00
abstract::Murine monoclonal antibodies against the fusion (F) and hemagglutinin-neuraminidase (HN) proteins of Sendai virus (SV) were prepared and studied on their antiviral activities, particularly on the neutralization of infectivity. On the analysis with solid phase competitive ELISA, 26 anti-HN antibodies were divided into ...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01316735
更新日期:1986-01-01 00:00:00
abstract::Mouse embryo fibroblasts and mouse adrenal tumor cells support the replication of encephalomyocarditis (EMC) virus, whereas rat glial and rat hepatoma cells are non-permissive. These differences in susceptibility were not due to the lack of virus attachment to rat cells. The findings that rat cells could be transfecte...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01310884
更新日期:1986-01-01 00:00:00
abstract::The in vitro cytopathology and the neurovirulence to inbred mice demonstrated by five variants originally derived from one laboratory strain (Miyama) of type 1 herpes simplex virus (HSV-1) were studied comparatively. Three of the variants are syncytial [+GC (LPV), +GC (SPV), +GC (81)] and two are non-syncytial [-GCr a...
journal_title:Archives of virology
pub_type: 杂志文章
doi:10.1007/BF01317369
更新日期:1986-01-01 00:00:00